Serena Williams extended her mastery over big sister Venus, and kept alive her bid for Grand Slam history.
In the 26th career meeting between the siblings, Serena dominated with her steady serve and big hitting from the back of the court to win 6-4, 6-3 on Centre Court in 1 hour, 8 minutes, extending her Grand Slam winning streak to 25 matches.
The win sent the top-ranked Serena into the Wimbledon quarterfinals as she bids for a fourth straight Grand Slam title, a feat last accomplished by the younger Williams in 2003.
Earlier, CoCo Vandeweghe reached the quarterfinals by upsetting French Open runner-up Lucie Safarova of the Czech Republic in straight sets.
Vandeweghe dominated both tiebreakers to win 7-6 (1), 7-6 (4) after the players traded breaks once in each set.
There will be three American women in the quarterfinals, as Madison Keys also advanced. It’s the first time three American women have reached the Wimbledon quarterfinals since Serena Williams, Lindsay Davenport and Jennifer Capriati did it in 2004.
Keys reached the Wimbledon quarterfinals for the first time. The 21st-seeded American beat Olga Govortsova of Belarus 3-6, 6-4, 6-1.
Keys, who reached the Australian Open semifinals this year, had never before been past the third round at Wimbledon.
Still looking for a second Wimbledon title, Maria Sharapova beat Zarina Diyas of Kazakhstan 6-4, 6-4 to set up a match against Vandeweghe. Sharapova won her first major title at Wimbledon in 2004.